Dominique Erni Selected Research

Hemorrhage

11/2006	Early resuscitation with polymerized bovine hemoglobin reverses acidosis, but not peripheral tissue oxygenation, in a severe hamster shock model.
6/2006	Rapid restoration of microcirculatory blood flow with hyperviscous and hyperoncotic solutions lowers the transfusion trigger in resuscitation from hemorrhagic shock.
3/2004	Improving microcirculation is more effective than substitution of red blood cells to correct metabolic disorder in experimental hemorrhagic shock.
6/2003	Resuscitation with polyethylene glycol-modified human hemoglobin improves microcirculatory blood flow and tissue oxygenation after hemorrhagic shock in awake hamsters.

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Dominique Erni Research Topics

Disease

6	Hypoxia (Hypoxemia) 08/2010 - 05/2003
5	Ischemia 05/2010 - 03/2005
5	Necrosis 12/2008 - 03/2005
4	Hemorrhage 11/2006 - 06/2003
4	Hemorrhagic Shock 06/2006 - 06/2003
3	Wounds and Injuries (Trauma) 07/2008 - 03/2005
2	Obesity 02/2011 - 05/2010
2	Diabetes Mellitus 02/2011 - 07/2008
2	Cardiovascular Diseases (Cardiovascular Disease) 02/2011 - 07/2008
2	Weight Loss (Weight Reduction) 05/2010 - 10/2003
2	Inflammation (Inflammations) 12/2008 - 03/2007
2	Shock 11/2006 - 06/2003
1	Hypotension (Low Blood Pressure) 04/2013
1	Pseudarthrosis (Pseudoarthrosis) 10/2010
1	Sciatic Neuropathy (Lesion of Sciatic Nerve) 05/2010
1	Breast Neoplasms (Breast Cancer) 02/2008
1	Acidosis 11/2006
1	Neoplasms (Cancer) 10/2005
1	Wound Infection (Wound Infections) 09/2005
1	Pain (Aches) 09/2005
1	Infections 09/2005
1	Critical Illness (Critically Ill) 03/2005
1	Septic Shock (Toxic Shock Syndrome) 01/2003
1	Sepsis (Septicemia) 01/2003

Drug/Important Bio-Agent (IBA)

4	Hemoglobins (Hemoglobin)IBA 03/2007 - 06/2003
4	Oxygen (Dioxygen)IBA 10/2005 - 06/2003
3	SolutionsIBA 03/2007 - 05/2003
3	Starch (Cornstarch)IBA 11/2006 - 01/2003
2	Colloids (Colloid)IBA 04/2013 - 06/2003
2	tin protoporphyrin IXIBA 04/2007 - 12/2005
2	Lactic Acid (Lactate)FDA LinkGeneric 10/2005 - 03/2005
2	Pyruvic Acid (Pyruvate)IBA 10/2005 - 03/2005
2	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 10/2004 - 06/2003
1	SteroidsIBA 02/2011
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 10/2010
1	Heme Oxygenase-1IBA 12/2008
1	Carbon MonoxideIBA 12/2008
1	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 12/2008
1	Messenger RNA (mRNA)IBA 10/2007
1	polymerized bovine hemoglobinIBA 11/2006
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 12/2005
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2005
1	LigandsIBA 10/2005
1	Small Interfering RNA (siRNA)IBA 10/2005
1	EphrinsIBA 10/2005
1	Eph Family Receptors (Eph Receptors)IBA 10/2005
1	monophosphoryl lipid AIBA 06/2005
1	Narcotics (Narcotic Analgesics)IBA 06/2005
1	Anesthetics (Anesthetic Agents)IBA 06/2005
1	Glucose (Dextrose)FDA LinkGeneric 03/2005
1	CarbohydratesIBA 03/2005
1	Human Serum Albumin FDA LinkGeneric 10/2004
1	AlbuminsIBA 10/2004
1	Bovine Serum AlbuminIBA 03/2004
1	Bosentan (Tracleer)FDA Link 01/2003
1	Endothelins (Endothelin)IBA 01/2003
1	Endothelin Receptor AntagonistsIBA 01/2003
1	Vasoconstrictor AgentsIBA 01/2003
1	Peptides (Polypeptides)IBA 01/2003

Therapy/Procedure

4	Resuscitation 11/2006 - 06/2003
2	Anesthesia 08/2010 - 06/2005
2	Free Tissue Flaps 05/2010 - 07/2008
2	Abdominoplasty 05/2010 - 10/2003
2	Myocutaneous Flap 09/2005 - 03/2005
1	Bone Transplantation (Bone Grafting) 10/2010
1	Bariatric Surgery 05/2010
1	Body Contouring 05/2010
1	Limb Salvage 07/2008
1	Aftercare (After-Treatment) 02/2008
1	Cardiac Surgical Procedures 09/2005
1	Lasers (Laser) 06/2005
1	Operative Time 10/2003
1	Hemodilution 05/2003
1	Intravenous Infusions 01/2003